Joint Research on Application of Antithrombogenic Thermoplastic Elastomer ‘ZELAS AMP’ to 놀이터 토토 사이트 Devices
October 8, 2025
Mitsubishi Chemical Corporation (Head Office: Chiyoda-ku, Tokyo; President: Manabu Chikumoto; hereafter ‘MCC’) has initiated a collaborative research project (hereinafter referred to as “the Joint Research”) in Partnership Chemistry and Engineering, Kyushu Univ. (Fukuoka City, Fukuoka Prefecture) and Profesor Shigeru Miyagawa of Osaka University Graduate school of medicine, Cardiovascular surgery (Suita City, Osaka Prefecture), focusing on application of our antithrombogenic 놀이터 토토 사이트. Through this Joint Research, MCC aims for market launch of ZELAS™ AMP in 2027 and its global expansion.
In 놀이터 토토 사이트 devices such as cardiac catheters and cardiopulmonary bypass circuits, anticoagulants have conventionally been coated onto the base resin to prevent blood coagulation and thrombus-related occlusion. However, since the cost of coa devices, there is demand for materials that can provide antithrombogenic properties at a lower cost.
MCC has accumulated advanced formulation and compounding technologies for the 놀이터 토토 사이트-grade compound resin ‘ZELAS™ AMP’ over many years and has expanded its global supply system for 놀이터 토토 사이트 materials※. The key polymer in ZELAS™ AMP is an amphiphilic polymer that combines blood compatibility, derived from its hydrophilic structure, with substrate affinity, derived from its hydrophobic structure. By adding this for 놀이터 토토 사이트 devices (such as polyvinyl chloride, polyurethane, and engineering plastics), antithrombogenic properties, low protein adsorption, and low bacterial adhesion can be imparted to the base material.
The Institute for Materials Chemistry and Engineering, Kyushu Univ. specializes in elucidating material structure and function from the atomic, molecular, and nanoscale to the macroscale, and has particular expertise in the surface design of 놀이터 토토 사이트 devices. Osaka University a world leader in research and development of advanced 놀이터 토토 사이트 fields such as heart transplantation, assisted circulation, and regenerative medicine.
In this Joint Research, MCC will pursue the optimal addition and formulation design of ZELAS™ AMP key polymer for various resins used as base materials for 놀이터 토토 사이트 devices. By developing ZELAS™ AMP in response to the needs of 놀이터 토토 사이트 professionals, MCC antithrombogenic properties and eliminate the need for coating processes, thereby lowering risk and manufacturing cost for 놀이터 토토 사이트 devices that come into direct contact with blood, such as cardiac catheters, cardiopulmonary bypass circuits, and dialysis and transfusion components.
MCC, under its management vision ‘KAITEKI Vision 35’, has designated technology and equipment for new therapeutics as one of its key business domains and aims to support new therapies with high-performance, 놀이터 토토 사이트-grade materials. Throu thermoplastic elastomer ‘ZELAS™ AMP’ in collaboration with healthcare professionals, MCC will contribute to improving the functionality and safety of blood-contacting 놀이터 토토 사이트 devices.
【About t놀이터 토토 사이트 Institute for Materials C놀이터 토토 사이트mistry and Engineering, Kyushu Univ.】
The Institute for Materials Chemistry and Engineering, Kyushu Univ. engages in a wide range of research, including synthesis of new functional molecules, the chemistry of novel molecular assemblies, the organic-inorganic hybrid materials, and the ch 놀이터 토토 사이트.
Professor Masaru Tanaka is a leading expert in bio놀이터 토토 사이트 materials and 놀이터 토토 사이트 device surface design. In this Joint Research, he will be responsible for evaluating the antithrombogenic properties of various 놀이터 토토 사이트 materials, including ZELAS™ AMP, and will provide analy leveraging his profound expertise in the creation and application of molecular assemblies and hybrid materials, he will support optimal material design.
【About Osaka University Graduate school of medicine, Cardiovascular surgery】
Osaka University Graduate school of medicine, Cardiovascular surgery has one of the nation’s leading track records in surgical procedures and is at the forefront both domestically and internationally in research and development of advanced 놀이터 토토 사이트 fields such surgery, regenerative medicine, and bio-design. Professor Shigeru Miyagawa is responsible for evaluating biocompatibility and antithrombogenicity using animal models that reflect clinical needs, as well as for conducting verification studies toward practical application. He has established a practical the 놀이터 토토 사이트 field.
※Acquisition of business from Welset Plast Extrusions Pvt. Ltd in India in 2019
/english/news_mcc/2018/1204623_7663.html
/english/news_mcc/2019/1206328_7665.html
Acquisition of business from AdvanSource Biomaterials Corporation in t놀이터 토토 사이트 United States in 2020
/english/news_mcc/2019/1207875_7665.html
In 놀이터 토토 사이트 devices such as cardiac catheters and cardiopulmonary bypass circuits, anticoagulants have conventionally been coated onto the base resin to prevent blood coagulation and thrombus-related occlusion. However, since the cost of coa devices, there is demand for materials that can provide antithrombogenic properties at a lower cost.
MCC has accumulated advanced formulation and compounding technologies for the 놀이터 토토 사이트-grade compound resin ‘ZELAS™ AMP’ over many years and has expanded its global supply system for 놀이터 토토 사이트 materials※. The key polymer in ZELAS™ AMP is an amphiphilic polymer that combines blood compatibility, derived from its hydrophilic structure, with substrate affinity, derived from its hydrophobic structure. By adding this for 놀이터 토토 사이트 devices (such as polyvinyl chloride, polyurethane, and engineering plastics), antithrombogenic properties, low protein adsorption, and low bacterial adhesion can be imparted to the base material.
The Institute for Materials Chemistry and Engineering, Kyushu Univ. specializes in elucidating material structure and function from the atomic, molecular, and nanoscale to the macroscale, and has particular expertise in the surface design of 놀이터 토토 사이트 devices. Osaka University a world leader in research and development of advanced 놀이터 토토 사이트 fields such as heart transplantation, assisted circulation, and regenerative medicine.
In this Joint Research, MCC will pursue the optimal addition and formulation design of ZELAS™ AMP key polymer for various resins used as base materials for 놀이터 토토 사이트 devices. By developing ZELAS™ AMP in response to the needs of 놀이터 토토 사이트 professionals, MCC antithrombogenic properties and eliminate the need for coating processes, thereby lowering risk and manufacturing cost for 놀이터 토토 사이트 devices that come into direct contact with blood, such as cardiac catheters, cardiopulmonary bypass circuits, and dialysis and transfusion components.
MCC, under its management vision ‘KAITEKI Vision 35’, has designated technology and equipment for new therapeutics as one of its key business domains and aims to support new therapies with high-performance, 놀이터 토토 사이트-grade materials. Throu thermoplastic elastomer ‘ZELAS™ AMP’ in collaboration with healthcare professionals, MCC will contribute to improving the functionality and safety of blood-contacting 놀이터 토토 사이트 devices.
【About t놀이터 토토 사이트 Institute for Materials C놀이터 토토 사이트mistry and Engineering, Kyushu Univ.】
The Institute for Materials Chemistry and Engineering, Kyushu Univ. engages in a wide range of research, including synthesis of new functional molecules, the chemistry of novel molecular assemblies, the organic-inorganic hybrid materials, and the ch 놀이터 토토 사이트.
Professor Masaru Tanaka is a leading expert in bio놀이터 토토 사이트 materials and 놀이터 토토 사이트 device surface design. In this Joint Research, he will be responsible for evaluating the antithrombogenic properties of various 놀이터 토토 사이트 materials, including ZELAS™ AMP, and will provide analy leveraging his profound expertise in the creation and application of molecular assemblies and hybrid materials, he will support optimal material design.
【About Osaka University Graduate school of medicine, Cardiovascular surgery】
Osaka University Graduate school of medicine, Cardiovascular surgery has one of the nation’s leading track records in surgical procedures and is at the forefront both domestically and internationally in research and development of advanced 놀이터 토토 사이트 fields such surgery, regenerative medicine, and bio-design. Professor Shigeru Miyagawa is responsible for evaluating biocompatibility and antithrombogenicity using animal models that reflect clinical needs, as well as for conducting verification studies toward practical application. He has established a practical the 놀이터 토토 사이트 field.
※Acquisition of business from Welset Plast Extrusions Pvt. Ltd in India in 2019
/english/news_mcc/2018/1204623_7663.html
/english/news_mcc/2019/1206328_7665.html
Acquisition of business from AdvanSource Biomaterials Corporation in t놀이터 토토 사이트 United States in 2020
/english/news_mcc/2019/1207875_7665.html
